研究领域（方向）
泌尿肿瘤学、材料医学、转化医学、医学人工智能、时空大数据。
个人及工作简历
李宁，中国医科大学附属第四医院泌尿外科副主任，教授、主任医师、硕士生导师，中国医科大学外科学博士，美国南卡罗莱纳大学访问学者。
中国医师协会泌尿外科分会肿瘤学组委员，中国中西医结合学会泌尿外科专业委员会转化医学学组委员，中国抗癌协会中西整合肾癌专委会委员，辽宁省医学会器官移植学分会委员，辽宁省医学会泌尿外科学分会尿控学组委员，辽宁省医学会泌尿外科学分会青年委员会委员，辽宁省医学会肾脏病学分会青年委员会委员，辽宁省抗癌协会肿瘤泌尿专业委员会青年委员会委员，沈阳医学会泌尿外科学分会委员，沈阳市高级人才，沈阳医学会医疗损害鉴定专家库成员。
主持省部级课题3项，以第一作者/通讯作者发表SCI收录论文20篇，累计影响因子50余分。
学术任职
（1）校内
2023-至今，主任医师
2019-至今，硕士生导师
2017-2023，副主任医师
（2）学会协会
中国医师协会泌尿外科分会肿瘤学组委员
中国中西医结合学会泌尿外科专业委员会转化医学学组委员
中国抗癌协会中西整合肾癌专委会委员
辽宁省医学会器官移植学分会委员
辽宁省医学会泌尿外科学分会尿控学组委员
辽宁省医学会泌尿外科学分会青年委员会委员
辽宁省医学会肾脏病学分会青年委员会委员
辽宁省抗癌协会肿瘤泌尿专业委员会青年委员会委员
沈阳市高级人才
沈阳医学会泌尿外科学分会委员
沈阳医学会医疗损害鉴定专家库成员
科研项目
[4] 辽宁省自然科学基金项目，构建天然多糖水凝胶支架及其重建输尿管相关机制研究，主持。
[3] 辽宁省教育厅科学研究经费项目（QN2019018），磷酸二酯酶4抑制剂对肥胖相关性膀胱功能障碍的治疗机制研究，2019.9-2021.12，主持。
[2] 辽宁省临床能力建设项目（LNCC-D16-2015），磷酸二酯酶4抑制剂治疗肥胖相关性膀胱过度活动症的应用项目，2015.8-2018.7，主持。
[1] 辽宁省自然科学基金项目（2015020493），调控磷酸二酯酶4B的上游MicroRNA在早期肥胖相关性膀胱功能障碍中的鉴定与作用研究，2015.8-2018.7，主持。
科研成果与学术论文
[20] Zuo, T., He, L., Zheng, Y., Lin, Z., Xu, Z., Li, N., Communication Analysis of
the COVID-19 Infodemic by Medical Practitioners in China: A Mixed Methods Study, Social Science &
Medicine, https://doi.org/10.1016/j.socscimed.2025.118051.
[19] Tan L, Zhang D, Li Y-x, Li Y, Guo T, Sun Y, Li N, Feng C. Identification of intratumor bacteria-associated prognostic risk score in adrenocortical carcinoma. Microbiol Spectr. 2024 Apr 2;12(4):e0372723. doi: 10.1128/spectrum.03727-23. Epub 2024 Feb 29. PMID: 38421176; PMCID: PMC10986527.
[18] Du H, Yin H, Qin Y, Min Y, Deng Q, Tan J, Li G, Li N, Zhu C, Xu Y. Subcellular Nanobionic Liposome with High Zeta Potential Enhances Intravesical Adhesion and Drug Delivery. ACS Nano. 2024 Jan 30;18(4):3583-3596. doi: 10.1021/acsnano.3c11235. Epub 2024 Jan 22. PMID: 38252681.
[17] Liu M, Hou J, Xu F, Du H, Liu J, Li N. Minimally invasive nephrolithotomy versus retrograde intrarenal surgery in surgical management of Lower calyceal stones: a systematic review with meta-analysis. Int J Surg. 2023 May 1;109(5):1481-1488. doi: 10.1097/JS9.0000000000000394. PMID: 37037590; PMCID: PMC10389464.
[16] Hou J, Xu F, Du H, Liu J, Li N. Efficacy and safety of the surgical treatments for lower calyceal stones: a systematic review and network meta-analysis. Int J Surg. 2023 Mar 1;109(3):383-388. doi: 10.1097/JS9.0000000000000062. PMID: 36906759; PMCID: PMC10389214.
[15] Du H, Xu F, Liu J, Zhang J, Qin Y, Xu Y, Li N. Long-term aspirin administration suppresses inflammation in diabetic cystopathy. Aging (Albany NY). 2023 Sep 12;15(17):9128-9143. doi: 10.18632/aging.205021. Epub 2023 Sep 12. PMID: 37702622; PMCID: PMC10522387.
[14] Xu F, Du H, Hou J, Liu J, Li N. Anti-inflammation properties of resveratrol in the detrusor smooth muscle of the diabetic rat. Int Urol Nephrol. 2022 Nov;54(11):2833-2843. doi: 10.1007/s11255-022-03334-x. Epub 2022 Aug 9. PMID: 35943662.
[13] Li J, Liu T, Li N, Dong F, Wang P. SKA-31-induced activation of small-conductance calcium-activated potassium channels decreased modulation of detrusor smooth muscle function in a rat model of obesity. J Bioenerg Biomembr. 2022 Jun;54(3):135-144. doi: 10.1007/s10863-022-09939-2. Epub 2022 Apr 27. PMID: 35478071.
[12] Wang L, Lyu Y, Li Y, Li K, Wen H, Feng C, Li N. ASXL1 promotes adrenocortical carcinoma and is associated with chemoresistance to EDP regimen. Aging (Albany NY). 2021 Sep 18;13(18):22286-22297. doi: 10.18632/aging.203534. Epub 2021 Sep 18. Erratum in: Aging (Albany NY). 2023 Oct 30;15(20):11690-11691. doi: 10.18632/aging.205255. PMID: 34536950; PMCID: PMC8507286.
[11] Hou J, He R, Li N, Liu Y, Wang P. Attenuated regulatory function of the small-conductance Ca2+-activated K+ channel in detrusor smooth muscle cells excitability in an obese rat model. Int Urol Nephrol. 2020 Oct;52(10):1851-1861. doi: 10.1007/s11255-020-02487-x. Epub 2020 May 12. PMID: 32399771.
[10] Li M, Liu Y, Liu J, Li W, Li N, Xue D, Zhang X, Wang P. Circ_0006332 promotes growth and progression of bladder cancer by modulating MYBL2 expression via miR-143. Aging (Albany NY). 2019 Nov 22;11(22):10626-10643. doi: 10.18632/aging.102481. Epub 2019 Nov 22. PMID: 31756170; PMCID: PMC6914401.
[9] Li N, Ding H, Zhang P, Li Z, Liu Y, Wang P. Attenuated BK channel function promotes overactive bladder in a rat model of obesity. Aging (Albany NY). 2019 Aug 21;11(16):6199-6216. doi: 10.18632/aging.102182. Epub 2019 Aug 21. PMID: 31480021; PMCID: PMC6738405.
[8] Gao ZM, Gao S, Qu HC, Li K, Li N, Liu CL, Zhu XW, Liu YL, Wang P, Zheng XH. Minimally invasive percutaneous nephrolithotomy improves stone-free rates for impacted proximal ureteral stones: A systematic review and meta-analysis. PLoS One. 2017 Feb 2;12(2):e0171230. doi: 10.1371/journal.pone.0171230. PMID: 28152097; PMCID: PMC5289591.
[7] Xin W, Li N, Fernandes VS, Petkov GV. Constitutively active PKA regulates neuronal acetylcholine release and contractility of guinea pig urinary bladder smooth muscle. Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1377-84. doi: 10.1152/ajprenal.00026.2016. Epub 2016 Mar 30. PMID: 27029424; PMCID: PMC4935771.
[6] Lan D, Qu HC, Li N, Zhu XW, Liu YL, Liu CL. The Value of Contrast-Enhanced Ultrasonography and Contrast-Enhanced CT in the Diagnosis of Malignant Renal Cystic Lesions: A Meta-Analysis. PLoS One. 2016 May 20;11(5):e0155857. doi: 10.1371/journal.pone.0155857. PMID: 27203086; PMCID: PMC4874594.
[5] Xin W, Li N, Fernandes VS, Chen B, Rovner ES, Petkov GV. BK channel regulation by phosphodiesterase type 1: a novel signaling pathway controlling human detrusor smooth muscle function. Am J Physiol Renal Physiol. 2016 May 15;310(10):F994-9. doi: 10.1152/ajprenal.00452.2015. Epub 2016 Feb 24. PMID: 26911851; PMCID: PMC5002058.
[4] Xue D, Zhang X, Zhang X, Liu J, Li N, Liu C, Liu Y, Wang P. Clinical significance and biological roles of TRIM24 in human bladder carcinoma. Tumour Biol. 2015 Sep;36(9):6849-55. doi: 10.1007/s13277-015-3393-3. Epub 2015 Apr 7. PMID: 25846736.
[3] Xin W, Li N, Cheng Q, Fernandes VS, Petkov GV. Constitutive PKA activity is essential for maintaining the excitability and contractility in guinea pig urinary bladder smooth muscle: role of the BK channel. Am J Physiol Cell Physiol. 2014 Dec 15;307(12):C1142-50. doi: 10.1152/ajpcell.00167.2014. Epub 2014 Oct 15. PMID: 25318105; PMCID: PMC4269660.
[2] Xin W, Li N, Cheng Q, Petkov GV. BK channel-mediated relaxation of urinary bladder smooth muscle: a novel paradigm for phosphodiesterase type 4 regulation of bladder function. J Pharmacol Exp Ther. 2014 Apr;349(1):56-65. doi: 10.1124/jpet.113.210708. Epub 2014 Jan 23. PMID: 24459245; PMCID: PMC3965888.
[1] Yili L, Yongzhi L, Ning L, Dongwei X, Chunlai L, Suomin L, Ping W. Flexible ureteroscopy and holmium laser lithotripsy for treatment of upper urinary tract calculi in patients with autosomal dominant polycystic kidney disease. Urol Res. 2012 Feb;40(1):87-91. doi: 10.1007/s00240-011-0390-x. Epub 2011 May 25. PMID: 21611814.
获奖及荣誉
[4] 中国医科大学附属第四医院优秀研究生导师（2023）
[3] 中国医科大学附属第四医院2021年度“最佳医生” （2021）
[2] 2017年度优秀援塔医疗专家
[1] 第三批优秀援塔干部人才
联系方式
电子邮箱：ningli@cmu.edu.cn
联系地址：辽宁省沈阳市皇姑区崇山东路4号中国医科大学附属第四医院泌尿外科